Causas del acné.

Different steps from the Acne

Acne, sometimes known as vulgar acne, is a chronic skin illness that affects the pilosebaceous unit (hair follicles and oil glands) and is marked by the appearance of comedones, papules, pustules, nodules, and scars on the face and upper trunk.

The main causes of acne.

During puberty, it is typical to acquire vulgaris acne.
Adults are more likely to develop Rosacea, which is a comparable characteristic.
The occurrence of vulgaris acne in older individuals can be the result of a secondary illness such as pregnancy, ovarian polycystic disease, or Cushing Syndrome.

The multiple origins and the mystery of why some people get acne while others don't, which is partly genetic

Acne and different Presentation
Acne and different Presentation








Causes of Acne

Increase in the production of oil and hyperplasia from the oil glands. Abnormal peeling from the keratinocyte. Bacteria  Propionibacterium acnes presence. Inflammation. Another cause of the presence of acne. Hormonal dysfunction, like the menstrual cycles in the puberty. Shrink from a follicular channel.

The abnormal spreading from the follicular cells, abnormal vincula cells between the follicle and the water retention in the skin, are mentioned like the important mechanism. Stress impulse triggers the discharge from the suprarenal glands.

Stages of Acne
         Stages of Acne and Production of oil


Hormonal Factor in the Development.

The main cause of seborrhea is overproduction of sebum, which is caused by hormonal releases.
Acne is caused by the interaction of many hormones.
Androgens, such as testosterone, dihydrotestosterone (DTH), and dehydroepiandrosterone sulfate, are the main regulators in the production oil (DHEAS).

Progesterone inhibits the enzyme 5-alpha reductase, which converts testosterone to the more potent dihydrotestosterone.
Estrogens shrink the sebaceous glands and reduce the amount of oil produced.
Insulin and the growth factor Insulin type 1 (IGF-1) are the insulin stimuli that cause the sebaceous glands to develop.
Adrenocorticotrophic hormone (ACTH) stimulates lipogenesis in the oil glands by converting to proopiomelanocortin in the anterior pituitary.

Proopiomelanocortin produces melacortines, which stimulate the sebaceous glands.
The adrenocorticotropic hormone stimulates oil production.
What Foods Are Acne-Producing?
There is speculation about the link between eating certain foods and the development of acne or the worsening of acne.

Chocolate, malt, sugar, or chemical substances, it was thought, could be linked to the worst acne scenario.
Only can there be a link between the severity of acne in children and teenagers who eat a high-fat, high-sugar diet.

When the type of skin is greasy, certain kind individuals present such a predisposition, which makes the situation worse.

Causes of Facial Acne and Distribution.

The presence of oil face type in complexity with the hormonal factors can develop this condition, with the appearance in the face and other areas of the body. there exists obstruction of the hair follicles (compound for the hair follicles and the pilosebaceous unit).

The excess of the production of oil starts around 9 years old that stimuli a high production of adrenal androgens and high levels of peeling from squamous epithelium that recover the interior of the follicles with the abnormal quaternization.

With obstruction from the follicular ostium. First in the microscopic way (microtomed). When the production of oil continues, the follicles it gets wide until it's visible the basic damage from the acne: the comedown.

Severe acne
Severe acne

The difference of a pimple is when existing the microscopic lesion (microtomed) inflammatory stage. Develop acne when microtomed grow and mature and break the skin show up the lesion in comedown. What causes the skin from the face breaks out.

The obstruction contributes to the super population to the bacteria's Propionibacterium acnes, which produce tissue inflammation. The present of immunology cells: lymphocyte TCD4 and neutrophils, which infiltrate the zone and disrupted the follicular wall, produce the follicles content; lipids, cellular content and fund bacterias to the surrounding dermis.

The inflammatory answer is extreme with the delivery from the mediator; cytokines, peptides and other, produce the apparition of the papule. To the mayor, inflammation conduces the formation of pustules and the extension and formation of a cyst.

The presence of nodules where exist deep inflammation and compound various hair follicles. This lesion produced skin scars.

 Acne Treatment.

The number of people that have acne, especially the teenager, present psychological and social alteration. In some cases, can develop a lack of confidence and can be depressed, because of low esteem and shame.

The treatment from acne depends on the extension e intensity from the disease, the production of scars, the factors from the patient like age, hormonal and skin characteristic.

Lastly from the history of the clinical answer to the diversity of treatment, also from the psychology that impacts in the life quality.

In general, the acne can be auto limited in the 60% of the cases and respond to combine therapies plus the topic treatment. In the 40% of the cases, the chronic acne and the severity can be prolonged until for more 12 years. Most of the cases are benefit the oral isotretinoin or you can cure naturally.

Actually, exist a wide diversity of treatment with drugs or medical procedures that allow to limited or resolved the damage from the skin. The application from one thyme solution can be alternative therapeutic and the use of benzoyl peroxide in the control of acne with bactericide power again the Propionibacterium acnes.

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